Advanced Lyophilization Technology Hub an industry-led partnership to advance the science and technology of lyophilization/freeze-drying. 

The goal of Advanced Lyophilization Technology Hub (LyoHUB) is to advance the science and technology of freeze-drying/lyophilization. LyoHUB’s members include companies in the pharmaceutical and food processing sectors, equipment manufacturers and university researchers, who combine their expertise and resources to accomplish the goal. Immediate objectives are:  (i) to identify and disseminate Best Practices for lyophilization equipment performance, testing and validation and (ii) to conduct applied research to advance lyophilization processes and products. 



What's Happening


  • LyoHUB app is now live on both App Store and Google Play Store!

    Download now to access our latest news, upcoming events, member information, open-access publications, and reports.

    But that's not all! Dive into our powerful lyophilization process optimization tool, LyoPRONTO, where you can:

    • Simulate freezing and primary drying performance for any process conditions and formulations.
    •  Evaluate cycle constraints based on primary drying space methodology.
    • Compute cycle parameters for the most optimal primary drying process.
    • Easily export or share results via email or text for further analysis.

    Get the app today and take control of your lyophilization process!

    Click below to download: 


Spotlights Archive


Feb 8, 2024

Did you know that solids can be crystalline or amorphous? 

It's interesting to note that lyophilization produces a solid powder or cake that exists in either crystalline or amorphous form. Crystalline solids have long-range molecular order, while amorphous solids lack long-range molecular order.

Learn more.

In the News

  • Rocket science for faster vaccines

    Jan 31, 2024

    Purdue researchers are bringing new freeze-drying methods to market, potentially slashing transportation costs This article sheds light on Purdue University's efforts to improve the freeze-drying process for pharmaceuticals. It emphasizes the challenges of the current freeze-drying process and how Purdue is working closely with industry members to respond to…

  • Advanced Manufacturing Technologies Designation Program | FDA

    Jan 19, 2024

    FDA encourages the early adoption of advanced manufacturing technologies (AMTs) that have the potential to benefit patients by improving manufacturing and supply dependability and optimizing…

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New Technologies

New Technologies Archive