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The goal of Advanced Lyophilization Technology Hub (LyoHUB) is to advance the science and technology of freeze-drying/lyophilization. LyoHUB’s members include companies in the pharmaceutical and food processing sectors, equipment manufacturers and university researchers, who combine their expertise and resources to accomplish the goal. Immediate objectives are: (i) to identify and disseminate Best Practices for lyophilization equipment performance, testing and validation and (ii) to conduct applied research to advance lyophilization processes and products.
What's Happening
Spotlight
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LyoHUB offers NEW Short Course on Pharmaceutical Freeze Drying, “Freeze Drying: Principles and Practice
The curriculum for this new course was designed by Dr. Steven Nail and Drew Strongrich, Research Scientist at LyoHUB.
Following completion of the "Freeze Drying: Principals and Practice" course, students will be able to:
- Identify and describe the three fundamental phases of the freeze-drying process.
- Outline key unit operations, processes, equipment, and process monitoring methods associated with the lyophilization of parenteral products.
- Describe product critical quality attributes, how they are measured, and the roles they play in short and long-term stability.
- Provide a broad overview of an approach to developing and optimizing a freeze-drying process, including the use of mathematical models for common formulations and containers.
- Discuss common deficiencies in the development and manufacturing of freeze-dried pharmaceuticals and provide information on current best-practices in industry.
Continuing Education Credit Available.
For more information and enrollment, visit http://www.eventreg.purdue.edu/online/lyophilization.
July 19, 2024
Residual gas analysis (RGA) can be used in pharmaceutical manufacturing to achieve a more comprehensive understanding of the freeze-drying process. RGA provides real-time insights into key variables, including leak detection and monitoring contaminants. For more on RGA in pharmaceutical lyophilization and experimental data from the LyoHUB demonstration facility, download the App Note prepared in partnership with innovative instrument provider, INFICON
https://lnkd.in/giy4KuVU
In the News
Events
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LyoSummerSchool registration sold out
LyoSummerSchool Registration sold out! June 11-12, 2024 at Purdue University This 2-day, hands-on intensive course will be taught by Steve Nail (LyoHUB Scientific Advisory Board member), G…
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March 26, 2024: LyoHUB Annual Meeting at the National Academies of Science, Washington D.C.
Celebrating the 10th Anniversary at the LyoHUB Annual Meeting 2024 LyoHUB members, hope you can join us at the LyoHUB Annual Meeting 2024 on March 26th in Washington D.C. We're thrilled to…
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April 14, 2023: AstraZeneca & LyoHUB host Inhaled Biologics Conference
AstraZeneca and LyoHUB present “Inhaled Biologics: Challenges, Opportunities, and Future Directions”, a 1-day conference to highlight the progress made in the delivery of…
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September, 2022: LyoHUB holds Annual Meeting and Roadmapping Workshop at Purdue University
In September, 2022 over 50 participants representing over 27 organizations gathered at Purdue University to hold our first Annual Meeting since the COVID pandemic began. We were honored to…
New Technologies
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Advancing Pharmaceutical Stability with Strain Gauges at LyoHUB
May 08, 2024Strain gauges are typically used to measure deformation or strain on an object. At the LyoHUB Demonstration Facility, thin film micromachined sensing elements are strategically placed on vials during…
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