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Advanced Lyophilization Technology Hub an industry-led partnership to advance the science and technology of lyophilization/freeze-drying. 

The goal of Advanced Lyophilization Technology Hub (LyoHUB) is to advance the science and technology of freeze-drying/lyophilization. LyoHUB’s members include companies in the pharmaceutical and food processing sectors, equipment manufacturers and university researchers, who combine their expertise and resources to accomplish the goal. Immediate objectives are:  (i) to identify and disseminate Best Practices for lyophilization equipment performance, testing and validation and (ii) to conduct applied research to advance lyophilization processes and products. 



What's Happening


  • LyoHUB offers NEW Short Course on Pharmaceutical Freeze Drying, “Freeze Drying: Principles and Practice

    The curriculum for this new course was designed by Dr. Steven Nail and Drew Strongrich, Research Scientist at LyoHUB.

    Following completion of the "Freeze Drying: Principals and Practice" course, students will be able to:

    • Identify and describe the three fundamental phases of the freeze-drying process.
    • Outline key unit operations, processes, equipment, and process monitoring methods associated with the lyophilization of parenteral products.
    • Describe product critical quality attributes, how they are measured, and the roles they play in short and long-term stability.
    • Provide a broad overview of an approach to developing and optimizing a freeze-drying process, including the use of mathematical models for common formulations and containers.
    • Discuss common deficiencies in the development and manufacturing of freeze-dried pharmaceuticals and provide information on current best-practices in industry.

    Continuing Education Credit Available.

    For more information and enrollment, visit


Spotlights Archive


May 28, 2024

LyoHUB's LyoSummerSchool Registration - Only a few spots remaining- REGISTRATION CLOSES THIS WEEK 6/1/24 or when capacity reached.
June 11-12, 2024 at Purdue University
This 2-day, hands-on intensive course will be taught by Steve Nail (LyoHUB Scientific Advisory Board member), Greg Sacha (SIMTRA) and Nick Huls (PostDoc, LyoHUB), plus several other vendor representatives and will including: hashtag
hashtag#FreezeDryMicroscopy The McCrone Group, Vial Filling and Rack Loading, Thermocouple procedures, Cake Appearance, Karl Fisher Metrohm USA, Best practices, Cycle Design/LyoPRONTO, Differential Scanning Calorimetry Mettler-Toledo International, Inc, Visual Inspection, Lyophilizer usage tips, Center vs. Edge Effect, Moisture Analysis. The course also features "Freeze Drying: Principles and Practice" online course to be taken before attending the event. The course will be offered only for registered LyoSummerSchool participants at a half price discounted rate of $600. The code to register for the discounted rate will be sent after conference registration. This online course has launched! For more information about the course, visit

Stay tuned for more updates

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