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The goal of Advanced Lyophilization Technology Hub (LyoHUB) is to advance the science and technology of freeze-drying/lyophilization. LyoHUB’s members include companies in the pharmaceutical and food processing sectors, equipment manufacturers and university researchers, who combine their expertise and resources to accomplish the goal. Immediate objectives are: (i) to identify and disseminate Best Practices for lyophilization equipment performance, testing and validation and (ii) to conduct applied research to advance lyophilization processes and products.
What's Happening
Spotlight
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LyoHUB launches the Lyo2040: Lyophilization and Freeze-Thaw Technology Roadmap for Pharma/Biotech Manufacturing.
October 4, 2024
Over the past two years, the Advanced Lyophilization Technology Hub (LyoHUB), with support from a National Institute of Standards and Technology (NIST) Advanced Manufacturing Technology Roadmap (MFGTech) grant, has collaborated with more than 100 pharmaceutical and life sciences manufacturing experts to develop the Lyo2040: Lyophilization and Freeze-Thaw Technology Roadmap for Pharma/Biotech Manufacturing.
The Lyo2040 roadmap builds on the first technology roadmap for lyophilization, the MFGTech-awarded Lyo2017 roadmap, to include:
- novel freeze-drying, aseptic (contamination-free) drying
- freeze-thaw technologies
- new product treatments like cell and gene therapies, nucleotides (building blocks of DNA and RNA), vaccines and therapeutics education/workforce development.
Advanced digital technologies will help achieve roadmap goals through automation and digitalization of the lyophilization process enabled by artificial intelligence, digital twins, big data, and data analytics.
To learn more, Click HERE
November 13, 2024
Purdue University is well represented today at the ASTM International's #Healthcare #Innovation Workshop in Orlando, identifying gaps and opportunities in this space. Great to brainstorm with ASTM International President and Purdue University Mechanical Engineering alumni, Andy Kireta and John Logar the Chair of ASTM International E55 Committee on #Pharmaceutical and #Biopharmaceutical Products with Jennifer Gray, Secretary of E55
In the News
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LyoHUB Unveils Lyo2040: A Comprehensive Lyophilization and Freeze-Thaw Technology Roadmap for Pharma and Biotech Manufacturing
Oct 04, 2024LyoHUB is proud to launch the Lyo2040: Lyophilization and Freeze-Thaw Technology Roadmap for Pharma/Biotech Manufacturing. We also wish a big thank you to the over 100 lyophilization experts who…
Events
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Lyo2040: Lyophilization and Freeze-Thaw Technology Roadmap for Pharma/Biotech Manufacturing.
You're invited to the next Giant Leap in pharmaceutical manufacturing research and training at Purdue. Please join us for the groundbreaking of the William D. and Sherry L. Young…
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LyoSummerSchool registration sold out
LyoSummerSchool Registration sold out! June 11-12, 2024 at Purdue University This 2-day, hands-on intensive course will be taught by Steve Nail (LyoHUB Scientific Advisory Board member), G…
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March 26, 2024: LyoHUB Annual Meeting at the National Academies of Science, Washington D.C.
Celebrating the 10th Anniversary at the LyoHUB Annual Meeting 2024 LyoHUB members, hope you can join us at the LyoHUB Annual Meeting 2024 on March 26th in Washington D.C. We're thrilled to…
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April 14, 2023: AstraZeneca & LyoHUB host Inhaled Biologics Conference
AstraZeneca and LyoHUB present “Inhaled Biologics: Challenges, Opportunities, and Future Directions”, a 1-day conference to highlight the progress made in the delivery of…
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September, 2022: LyoHUB holds Annual Meeting and Roadmapping Workshop at Purdue University
In September, 2022 over 50 participants representing over 27 organizations gathered at Purdue University to hold our first Annual Meeting since the COVID pandemic began. We were honored to…
New Technologies
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Multipoint Temperature Sensor/Virtual Thermocouple
Oct 01, 2024Monitoring product temperature during lyophilization is critical, especially during the process development stage, as the final product may be jeopardized if its process temperature exceeds a…
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Lyo Launchpad and Corning Unveil Innovative Wireless Sensor Technology for Enhanced Lyophilization Monitoring
Sep 01, 2024State-of-the-art wireless sensors offer real-time insights, improving efficiency and product quality in the pharmaceutical industry Lyo Launchpad and Corning have collaborated to develop an innovative wireless…
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Advancing Pharmaceutical Stability with Strain Gauges at LyoHUB
May 07, 2024Strain gauges are typically used to measure deformation or strain on an object. At the LyoHUB Demonstration Facility, thin film micromachined sensing elements are strategically placed on vials during…
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Creating the Next Generation of Stable mRNA Vaccines: From -80 oC Freezers to Room Temperature Storage
Jul 30, 2022Purdue research hub to transform freeze-drying process used to make lifesaving drugs, preserve food Funded by: NIIMBL (National Institute for Innovation in Manufacturing Biopharmaceuticals) as…
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