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  1. Inter- and Intra- Tablet Coating Variability

    18 Dec 2007 | Animations | Contributor(s): Carl Wassgren

    Tablets are coated for a number of reasons, the most important of which is controlling the release profiles and bioavailability of the active pharmaceutical ingredient. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form.Tablets are usually...

  2. Introduction to API Process Simulation

    15 Sep 2009 | Teaching Materials | Contributor(s): Kamal Kuriyan

    This module describes model building methods and tools that can be used to simulate unit operations in pharmaceutical API processes. The use of simulation tools is introduced through simulations of heat transfer and fed batch reaction. Models of unit operations are constructed from the balance...

  3. Introduction to CFD

    18 Dec 2018 | Online Presentations | Contributor(s): David Russ

  4. Introduction to Mixing Equipment and Processes in Pharmaceutical Operations

    13 Feb 2009 | Teaching Materials | Contributor(s): Piero Armenante, Henrik Pedersen

    An ERC SOPS educational module. This powerpoint presentation provides an introduction to the pharmaceutical processing equipment used for liquid-liquid and liquid-solid mixing. The principles of single and multiphase mixing in pharmaceutical processes are introduced along with methods to analyze...

  5. Introduction to Model Building

    08 May 2008 | Online Presentations | Contributor(s): Gary Blau

    Course Background:Initial ideas developed for Pharmaceutical Scientists at the Dow Chemical Plant in Brindisi, Italy (1975)Subsequently evolved into a global course on Process Optimization presented to Dow Scientists and engineers in Europe and North America.Morphed into two courses in the...

  6. Introduction to solid dosage processing

    24 Jul 2013 | Teaching Materials | Contributor(s): Kamal Kuriyan

    This module provides an introduction to solid dosage processing. It highlights the importance of particle properties and their potential impact on the quality attributes of the dosage form. Unit operations and granulation processes that can be used to control particle properties are described....

  7. Introduction to the Rheology of Complex Fluids

    12 Feb 2010 | Teaching Materials | Contributor(s): Aldo Acevedo, Henrik Pedersen

    This module contains PowerPoint presentations aimed at providing the necessary background to understand, perform and interpret experimental rheological characterization of complex fluids. An overview of rheology is presented in the first part. Next, the available instrumentation and typical flows...

  8. Jos Corver lecture on Continuous Freeze Drying

    14 Feb 2019 | Online Presentations | Contributor(s): Jos Corver

    Jos Corver December 2018 lecture on Continuous Freeze Drying for LyoHUB at Purdue University can be viewed at   ABSTRACT: The guidelines of FDA’s PAT mention the need for continuous processing in pharma to achieve a mechanism of 100%...

  9. Jupyter Notebook (2020)

    11 May 2022 | Tools | Contributor(s): Steven Clark

    Starts the Jupyter notebook server

  10. Jupyter Notebook (hub version 6.0)

    10 Jun 2020 | Tools | Contributor(s): Steven Clark

    Jupyter notebook running in anaconda-6 environment

  11. Kinetic workshop simple degradation scheme

    17 Dec 2013 | Tools | Contributor(s): Lee Kirsch, Stephen Dion Stamatis

    Simulates simple pH-dependent drug degradation process

  12. Kirsch morning presentation ppoint2003

    29 Oct 2010 | Online Presentations | Contributor(s): Lee Kirsch

  13. LCA approach to the analysis of solvent waste issues in the pharmaceutical industry

    09 Jul 2013 | Online Presentations | Contributor(s): Michael Raymond, C. Stewart Slater, Mariano J. Savelski

    Life cycle assessment offers a unique opportunity to analyze emission reductions across all manufacturing sectors. However, few efforts have been made to apply this method to the pharmaceutical industry. Typically, between 80 and 90% of the total mass used in the production of an active...

  14. Level Set Dissolution

    21 Feb 2008 | Tools | Contributor(s): Dan Braido, Alberto Cuitino, Ann Christine Catlin

    Level Set Dissolution Description

  15. Life Cycle Analysis of Biobased Pennakem's ecoMeTHF™ : Green Solvents for the Pharmaceutical and Fine Chemical Industry

    09 Jul 2013 | Online Presentations | Contributor(s): Mariano Savelski, C. Stewart Slater, Dave Aycock, Bogdan Comanita, Steve Prescott, Jeff Shifflette, Rowan University

    An environmental analysis has been conducted to determine the life cycle emissions to manufacture the green solvent, 2-methyltetrahydrofuran. Analyses have been performed using different methods to show greenness in both its production and industrial use. This solvent has the potential as a...

  16. Life Cycle Analysis with Application to Consumer Products and Pharmaceuticals

    28 Nov 2011 | Teaching Materials | Contributor(s): C. Stewart Slater

    This is a three session module on introduction to performing and interpreting a life cycle analysis using consumer product and pharmaceutical manufacturing examples. Session 1 is an overview of the basic concepts of life cycle analysis. This includes the basics of process modeling and an...

  17. Liquid Mixing Fundamentals

    13 Feb 2009 | Teaching Materials | Contributor(s): Piero Armenante, Henrik Pedersen

    An ERC SOPS educational module. This powerpoint presentation provides background to identify the geometric, physical and dynamic variables of importance for the analysis of mixing in a stirred tank. It inroduces methods to assess the relative importance of those variables and toquantify the power...

  18. Lyo Chamber Pressure Variation Calculator

    05 Mar 2015 | Tools | Contributor(s): Alina Alexeenko, Nikhil Varma

    Calculates pressure variation within freeze-dryer shelf as a function of intershelf gap, shelf size and sublimation flux

  19. LyoCalculator

    10 Jun 2009 | Tools | Contributor(s): Stan Karpuk, Gayathri Shivkumar, Linas Mockus, Alina Alexeenko

    Predict product temperature during primary drying

  20. LyoHUB Annual Report 2019

    07 Apr 2020 | Publications | Contributor(s): Jennifer Gray

    Annual Report for the LyoHUB Consortium for 2019