-
LyoHUB Membership presentation
01 Oct 2020 | Online Presentations | Contributor(s): Jennifer Gray
slides for those interested in membership
-
LyoHUB brochure V2
01 Oct 2020 | Publications | Contributor(s): Jennifer Gray
brochure created in 2020
-
LyoHUB Annual Report 2020
01 Oct 2020 | Publications | Contributor(s): Jennifer Gray
The LyoHUB annual report for 2020
-
Jupyter Notebook (hub version 6.0)
10 Jun 2020 | Tools | Contributor(s): Steven Clark
Jupyter notebook running in anaconda-6 environment
-
Lyophilization in Review 2019
28 Apr 2020 | Publications | Contributor(s): Jennifer Gray
Summary: In 2019, the U.S. FDA approved a total of 47 lyophilized drug applications submitted by 37 companies. Information on generic drugs was compiled from FDA’s Orange Book database, not including drugs listed with any of the following conditions: discontinued, solution dosage...
-
LyoHUB Annual Report 2019
07 Apr 2020 | Publications | Contributor(s): Jennifer Gray
Annual Report for the LyoHUB Consortium for 2019
-
2019 LyoHUB Annual Report
07 Jun 2019 | Publications | Contributor(s): Jennifer Gray
-
Jos Corver lecture on Continuous Freeze Drying
14 Feb 2019 | Online Presentations | Contributor(s): Jos Corver
Jos Corver December 2018 lecture on Continuous Freeze Drying for LyoHUB at Purdue University can be viewed at http://www.kaltura.com/tiny/z0puf ABSTRACT: The guidelines of FDA’s PAT mention the need for continuous processing in pharma to achieve a mechanism of 100%...
-
Recommended Best Practices for Process Instrumentation in Freeze Drying
28 Jan 2019 | Online Presentations | Contributor(s): Steven L Nail
-
Fundamentals of Freeze Drying: A Brief Review and Commentary
11 Jan 2019 | Online Presentations | Contributor(s): Steven L Nail
-
Introduction to CFD
18 Dec 2018 | Online Presentations | Contributor(s): David Russ
-
Fundamentals of Freeze Drying II: The Freezing Process
18 Dec 2018 | Online Presentations | Contributor(s): Steven L Nail
OutlineThe Freezing ProcessSupercooling and ice nucleationCharacterization of freezing behaviorEstablishment of upper product temperature limit during primary drying
-
Fundamentals of Freeze Drying
12 Dec 2018 | Courses | Contributor(s): Steven L Nail
Lyo-Hub Summer School
-
Fundamentals of Freeze Drying V: Formulation Consderations
30 Nov 2018 | Online Presentations | Contributor(s): Steven L Nail
-
Fundamentals of Freeze Drying IV: Process Monitoring
30 Nov 2018 | Online Presentations | Contributor(s): Steven L Nail
-
Fundamentals of Freeze Drying III: Primary and Secondary Drying
30 Nov 2018 | Online Presentations | Contributor(s): Steven L Nail
OutlinePrimary dryingHeat transfer considerationsMeasurement of the vial heat transfer coefficientMass transfer considerationsMeasurement of the resistance of the dried product layerSecondary dryingCritical process variables during secondary dryingHow dry is “dry enough”
-
Fundamentals of Freeze Drying I: Introduction and Process Overview
30 Nov 2018 | Online Presentations | Contributor(s): Steven L Nail
Outline Introduction Advantages and limitations of freeze drying Product quality attributes Process overview Freezing Primary drying Secondary drying The Freezing Process Supercooling and ice nucleation Characterization of freezing...
-
Progress in Vacuum Pressure Measurement
08 Nov 2018 | Online Presentations | Contributor(s): Martin Wuest
For many years standard vacuum pressure measurement sensors consist of capacitance diaphragm gauges, Pirani heat transfer gauges as well as ionization gauges. Development has progressed from passive gauges with a detached controller to combination gauges with integrated electronics. Market...
-
Dr. Michael Pikal presentation "Modeling in Freeze-Drying:Past, Current State and Future Perspectives"
27 Jun 2018 | Online Presentations
Early Work by Marcus KarelMotivation for Modeling StudiesStead State ModelsThe Non-Steady State Model in Two DimensionsNon-Steady Models for Sublimation and Desorption DryingThe Nonsteady State Modeling of Freeze Drying: In-Process Product Temperature and Moisture Content...
-
SafeRx Spreadsheets for Mapping Between Data Sources
16 Jan 2018 | Downloads
Spreadsheets for mapping between data sources. Each spreadsheet contains one column listing the identifiers from a specific data source. Two spreadsheets can then be used by CMSA to create a mapping between the identifiers of different sources. Mappings can be one-to-one, many-to-one, or...