Dr. Michael Pikal presentation "Modeling in Freeze-Drying:Past, Current State and Future Perspectives"

27 Jun 2018

Early Work by Marcus KarelMotivation for Modeling StudiesStead State ModelsThe Non-Steady State Model in Two DimensionsNon-Steady Models for Sublimation and Desorption DryingThe Nonsteady State Modeling of Freeze Drying: In-Process Product Temperature and Moisture Content...

Drug Delivery Experiments

17 Oct 2012 | Downloads

Attached are five files detailing four separate experiments that are designed to be used in an undergraduate curriculum. The alginate bead experiment utilizes an alginate hydrogel drug delivery system to affect the rate at which a dye or protein is released. The lozenge experiment is a drug...

Distillation Viewer for Multicomponent Separations

09 Nov 2024 | Tools

Graphical interface to examine configurations generated by NLP distillation optimization

Advance Process Control I

09 Nov 2024 | Online Presentations

Advance Process Control I

09 Nov 2024 | Online Presentations

This module presentation will:- clarifying the difference between control and optimization.- go through the basic control so that the students refresh their basic knowledge of control.- develop a qualitative principles-based models to gain insights of the inputs and its relationships with the...

Solid-Liquid Separations

09 Nov 2024 | Teaching Materials

This module covers topics related to solid-liquid separations:Flow in packed beds.Cake filtration.Centrifuges.Deliquoring and washing.

Applications: Solvent Switching

09 Nov 2024 | Teaching Materials

This module presents an application of a simulation model in API process development and design. The application involves the use of a simulation model to compare feed profiles for solvent switching in a batch vessel.ERC for Structured Organic Particulate Systems

Batch Distillaton Basics

09 Nov 2024 | Teaching Materials

This module introduces topics related to batch distillation:Vapor-liquid equilibrium.Single stage distillation.Column configuration and operating policies.Simulation and design of distillation columns.Girish Joglekar

Introduction to API Process Simulation

09 Nov 2024 | Teaching Materials

This module describes model building methods and tools that can be used to simulate unit operations in pharmaceutical API processes. The use of simulation tools is introduced through simulations of heat transfer and fed batch reaction. Models of unit operations are constructed from the balance...

Analysis of Cake Filtration

09 Nov 2024 | Tools

Filtration calculation for different types of filter cake

Compartment Modeling

09 Nov 2024 | Tools

Compartment Modeling Description

Dynamic Simulation of Roller Compaction

09 Nov 2024 | Publications

A dynamic model for roller compaction process is derived based on Johanson’s rolling theory and material balance. Johanson’s rolling theory is used to predict the stress and density profiles during the compaction and the material balance equation describes the roll gap change. The proposed model...

Dynamic Roller Compactor

09 Nov 2024 | Tools

Dynamic simulation of roller compaction for dry granulation

High Shear Mixer

09 Nov 2024 | Tools

Analyze particles as they move through a high shear mixer

Roller Compactor

09 Nov 2024 | Tools

Calculate nip angle, normal and shear stresses for roller compactor using Johanson's model