Discrete Element Method (DEM) Course Module

02 Jul 2024 | Courses

The DEM course module was created by Carl Wassgren of the Particulate Systems Laboratory (PSL) at Purdue University. The series consists of slides and videos that will familiarize you with the basics of DEM. Discrete Element Method has been applied to analyze and predict flow behaviour in a wide...

Guidelines Viewer

02 Jul 2024 | Tools

View Guidelines in Ontology Browser

High Shear Mixer

02 Jul 2024 | Tools

Analyze particles as they move through a high shear mixer

Hopper Flow Discharge

02 Jul 2024 | Tools

DEM simulation of the discharge of particles from a hopper

Hopper Segregation

02 Jul 2024 | Animations

The Particulate Sciences Laboratory at Purdue University investigates the mixing and segregation of binary and multi-component granular materials. Solids mixing, also known as blending, is a common processing operation used in the manufacture of pharmaceutical products. The intent of mixing...

Information Representation in POPE

02 Jul 2024 | Online Presentations

The development of a pharmaceutical product requires the collection of information during pre-formulation studies, product formulation, process development, scaleup and manufacturing. A large amount of information of different types, ranging from raw data to lab reports to sophisticated math...

Inter- and Intra- Tablet Coating Variability

02 Jul 2024 | Animations

Tablets are coated for a number of reasons, the most important of which is controlling the release profiles and bioavailability of the active pharmaceutical ingredient. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form.Tablets are usually...

Navigating the POPE Ontology

02 Jul 2024 | Publications

What knowledge is included in POPE? There are three knowledge components: guideline knowledge, mathematical knowledge and information representations. The guideline knowledge component includes representations of actions and decisions. The mathematical knowledge component includes descriptions of...

Ontological informatics infrastructure for pharmaceutical product development

02 Jul 2024 | Publications

Informatics infrastructure plays a crucial role in supporting different decision making activities related to pharmaceutical product development, pilot plant and commercial scale manufacturing by streamlining information gathering, data integration, model development and managing all these for...

Ontological Informatics Infrastructure: An Overview

02 Jul 2024 | Online Presentations

Pharmaceutical product development involves managing a large amount of information and knowledge in different formats. Ontological informatics is used to represent and integrate the information and knowledge and support product development applications.Venkat Venkatasubramanian,Chunhua Zhao,...

ParticleVis: A Tool for DEM Particle Visualization

02 Jul 2024 | Downloads

ParticleVis is a visualization tool specialized for loading and exploring particulate simulation data. It contains a set of features that enables powerful and useful visualizations of particle simulations to be quickly generated. Support is provided for visualization of hundreds of thousands of...

Pharmaceutical Informatics

02 Jul 2024 | Series

Pharmaceutical products manufacturing is an important growth area for the US economy. Continued progress in biotechnology and genetic engineering coupled with an aging population will create both new mega-opportunities as well as pose new major challenges in this area, where the products are...

Product Formulation

02 Jul 2024 | Online Presentations

Pharmaceutical product development involves drug discovery,development of the drug substance (for improved processibility and absorption), anddevelopment of the drug product (identity and amount of excipients, choice of manufacturing platform or process).Product development requires access to...

PSL DEM Lecture 01: Motivation

02 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 01: Motivation.

PSL DEM Lecture 02: Hard Particle Collision Modeling

02 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 02: Hard Particle Collision Modeling

PSL DEM Lecture 03: Hard Particle Contact Detection

02 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 03: Hard Particle Contact Detection.

PSL DEM Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I

02 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I.

PSL DEM Lecture 07: Normal Contact Force Models - Part II

02 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 07: Normal Contact Force Models - Part II.

PSL DEM Lecture 09: Tangential Contact Force Models

15 May 2008 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 9: Tangential Contact Force Models.

PSL DEM Lecture 11: Coarse Contact Detection

02 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 11: Coarse Contact Detection.