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Discrete Element Method (DEM) Course Module
20 Oct 2024 | Courses
The DEM course module was created by Carl Wassgren of the Particulate Systems Laboratory (PSL) at Purdue University. The series consists of slides and videos that will familiarize you with the basics of DEM. Discrete Element Method has been applied to analyze and predict flow behaviour in a wide...
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Drug Delivery Experiments
20 Oct 2024 | Downloads
Attached are five files detailing four separate experiments that are designed to be used in an undergraduate curriculum. The alginate bead experiment utilizes an alginate hydrogel drug delivery system to affect the rate at which a dye or protein is released. The lozenge experiment is a drug...
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Guidelines Viewer
20 Oct 2024 | Tools
View Guidelines in Ontology Browser
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High Shear Mixer
20 Oct 2024 | Tools
Analyze particles as they move through a high shear mixer
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Hopper Flow Discharge
20 Oct 2024 | Tools
DEM simulation of the discharge of particles from a hopper
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Hopper Segregation
20 Oct 2024 | Animations
The Particulate Sciences Laboratory at Purdue University investigates the mixing and segregation of binary and multi-component granular materials. Solids mixing, also known as blending, is a common processing operation used in the manufacture of pharmaceutical products. The intent of mixing...
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Information Representation in POPE
20 Oct 2024 | Online Presentations
The development of a pharmaceutical product requires the collection of information during pre-formulation studies, product formulation, process development, scaleup and manufacturing. A large amount of information of different types, ranging from raw data to lab reports to sophisticated math...
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Inter- and Intra- Tablet Coating Variability
20 Oct 2024 | Animations
Tablets are coated for a number of reasons, the most important of which is controlling the release profiles and bioavailability of the active pharmaceutical ingredient. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form.Tablets are usually...
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Navigating the POPE Ontology
20 Oct 2024 | Publications
What knowledge is included in POPE? There are three knowledge components: guideline knowledge, mathematical knowledge and information representations. The guideline knowledge component includes representations of actions and decisions. The mathematical knowledge component includes descriptions of...
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Ontological informatics infrastructure for pharmaceutical product development
20 Oct 2024 | Publications
Informatics infrastructure plays a crucial role in supporting different decision making activities related to pharmaceutical product development, pilot plant and commercial scale manufacturing by streamlining information gathering, data integration, model development and managing all these for...
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Ontological Informatics Infrastructure: An Overview
20 Oct 2024 | Online Presentations
Pharmaceutical product development involves managing a large amount of information and knowledge in different formats. Ontological informatics is used to represent and integrate the information and knowledge and support product development applications.Venkat Venkatasubramanian,Chunhua Zhao,...
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ParticleVis: A Tool for DEM Particle Visualization
20 Oct 2024 | Downloads
ParticleVis is a visualization tool specialized for loading and exploring particulate simulation data. It contains a set of features that enables powerful and useful visualizations of particle simulations to be quickly generated. Support is provided for visualization of hundreds of thousands of...
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Pharmaceutical Informatics
20 Oct 2024 | Series
Pharmaceutical products manufacturing is an important growth area for the US economy. Continued progress in biotechnology and genetic engineering coupled with an aging population will create both new mega-opportunities as well as pose new major challenges in this area, where the products are...
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Product Formulation
20 Oct 2024 | Online Presentations
Pharmaceutical product development involves drug discovery,development of the drug substance (for improved processibility and absorption), anddevelopment of the drug product (identity and amount of excipients, choice of manufacturing platform or process).Product development requires access to...
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PSL DEM Lecture 01: Motivation
20 Oct 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 01: Motivation.
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PSL DEM Lecture 02: Hard Particle Collision Modeling
20 Oct 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 02: Hard Particle Collision Modeling
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PSL DEM Lecture 03: Hard Particle Contact Detection
20 Oct 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 03: Hard Particle Contact Detection.
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PSL DEM Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I
20 Oct 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I.
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PSL DEM Lecture 07: Normal Contact Force Models - Part II
20 Oct 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 07: Normal Contact Force Models - Part II.
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PSL DEM Lecture 09: Tangential Contact Force Models
15 May 2008 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 9: Tangential Contact Force Models.