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Discrete Element Method (DEM) Course Module
18 Aug 2024 | Courses
The DEM course module was created by Carl Wassgren of the Particulate Systems Laboratory (PSL) at Purdue University. The series consists of slides and videos that will familiarize you with the basics of DEM. Discrete Element Method has been applied to analyze and predict flow behaviour in a wide...
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Drug Delivery Experiments
18 Aug 2024 | Downloads
Attached are five files detailing four separate experiments that are designed to be used in an undergraduate curriculum. The alginate bead experiment utilizes an alginate hydrogel drug delivery system to affect the rate at which a dye or protein is released. The lozenge experiment is a drug...
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Factorial Experimentation
05 May 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar
A full factorial experiment is a set of experimental runs such that all levels of a given factor are combined with all levels of every other factor.
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High Shear Mixer
18 Aug 2024 | Tools
Analyze particles as they move through a high shear mixer
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Hopper Flow Discharge
18 Aug 2024 | Tools
DEM simulation of the discharge of particles from a hopper
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Hopper Segregation
18 Aug 2024 | Animations
The Particulate Sciences Laboratory at Purdue University investigates the mixing and segregation of binary and multi-component granular materials. Solids mixing, also known as blending, is a common processing operation used in the manufacture of pharmaceutical products. The intent of mixing...
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Inter- and Intra- Tablet Coating Variability
18 Aug 2024 | Animations
Tablets are coated for a number of reasons, the most important of which is controlling the release profiles and bioavailability of the active pharmaceutical ingredient. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form.Tablets are usually...
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Introduction to Model Building
18 Aug 2024 | Online Presentations | Contributor(s): Carl Wassgren, Avik Sarkar
Course Background:Initial ideas developed for Pharmaceutical Scientists at the Dow Chemical Plant in Brindisi, Italy (1975)Subsequently evolved into a global course on Process Optimization presented to Dow Scientists and engineers in Europe and North America.Morphed into two courses in the...
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ParticleVis: A Tool for DEM Particle Visualization
18 Aug 2024 | Downloads
ParticleVis is a visualization tool specialized for loading and exploring particulate simulation data. It contains a set of features that enables powerful and useful visualizations of particle simulations to be quickly generated. Support is provided for visualization of hundreds of thousands of...
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Probability Theory Review
05 May 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar
For any real system or phenomenon, there will be a certain amount of variability associated with data generated by the system.Probability is the language used to characterize and interpret the variability of this data.Probability is the most widely used formalism for quantifying uncertainty.
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Problems for Statistical Model Building
05 May 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar
Scenarios, problem statements, JMP data files, and solutions for the course on Statistical Model Building and Design of Experiments. Scenario 1 is based on a batch reactor system for small molecule API production. Scenario 2 is based on a test-bed to study the feasibility of continuous operation...
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PSL DEM Lecture 01: Motivation
18 Aug 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 01: Motivation.
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PSL DEM Lecture 02: Hard Particle Collision Modeling
18 Aug 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 02: Hard Particle Collision Modeling
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PSL DEM Lecture 03: Hard Particle Contact Detection
18 Aug 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 03: Hard Particle Contact Detection.
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PSL DEM Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I
18 Aug 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I.
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PSL DEM Lecture 07: Normal Contact Force Models - Part II
18 Aug 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 07: Normal Contact Force Models - Part II.
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PSL DEM Lecture 09: Tangential Contact Force Models
15 May 2008 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 9: Tangential Contact Force Models.
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PSL DEM Lecture 11: Coarse Contact Detection
18 Aug 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 11: Coarse Contact Detection.
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PSL DEM Lecture 13: 3D Rotations
18 Aug 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 13: 3D Rotations.
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Response Surface Methodology
05 May 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar
This lecture describes response surface models:Models are simple polynomialsInclude terms for interaction and curvatureCoefficients are usually established by regression analysis with a computer programInsignificant terms are discarded