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Advance Process Control I
08 Feb 2011
This module presentation will:- clarifying the difference between control and optimization.- go through the basic control so that the students refresh their basic knowledge of control.- develop a qualitative principles-based models to gain insights of the inputs and its relationships with the...
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Advance Process Control I
26 Jan 2012
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Analysis of Cake Filtration
25 Aug 2024 | Tools
Filtration calculation for different types of filter cake
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Applications: Solvent Switching
25 Aug 2024 | Teaching Materials
This module presents an application of a simulation model in API process development and design. The application involves the use of a simulation model to compare feed profiles for solvent switching in a batch vessel.ERC for Structured Organic Particulate Systems
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Batch Distillaton Basics
25 Aug 2024 | Teaching Materials
This module introduces topics related to batch distillation:Vapor-liquid equilibrium.Single stage distillation.Column configuration and operating policies.Simulation and design of distillation columns.Girish Joglekar
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Compartment Modeling
25 Aug 2024 | Tools
Compartment Modeling Description
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Discrete Element Method (DEM) Course Module
25 Aug 2024 | Courses
The DEM course module was created by Carl Wassgren of the Particulate Systems Laboratory (PSL) at Purdue University. The series consists of slides and videos that will familiarize you with the basics of DEM. Discrete Element Method has been applied to analyze and predict flow behaviour in a wide...
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Distillation Viewer for Multicomponent Separations
25 Aug 2024 | Tools
Graphical interface to examine configurations generated by NLP distillation optimization
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Dr. Michael Pikal presentation "Modeling in Freeze-Drying:Past, Current State and Future Perspectives"
27 Jun 2018 | Online Presentations
Early Work by Marcus KarelMotivation for Modeling StudiesStead State ModelsThe Non-Steady State Model in Two DimensionsNon-Steady Models for Sublimation and Desorption DryingThe Nonsteady State Modeling of Freeze Drying: In-Process Product Temperature and Moisture Content...
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Drug Delivery Experiments
17 Oct 2012 | Downloads
Attached are five files detailing four separate experiments that are designed to be used in an undergraduate curriculum. The alginate bead experiment utilizes an alginate hydrogel drug delivery system to affect the rate at which a dye or protein is released. The lozenge experiment is a drug...
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Dynamic Roller Compactor
25 Aug 2024 | Tools
Dynamic simulation of roller compaction for dry granulation
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Dynamic Simulation of Roller Compaction
25 Aug 2024 | Publications
A dynamic model for roller compaction process is derived based on Johanson’s rolling theory and material balance. Johanson’s rolling theory is used to predict the stress and density profiles during the compaction and the material balance equation describes the roll gap change. The proposed model...
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High Shear Mixer
25 Aug 2024 | Tools
Analyze particles as they move through a high shear mixer
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High Shear Mixer
25 Aug 2024 | Tools
Analyze particles as they move through a high shear mixer
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Hopper Flow Discharge
25 Aug 2024 | Tools
DEM simulation of the discharge of particles from a hopper
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Hopper Segregation
25 Aug 2024 | Animations
The Particulate Sciences Laboratory at Purdue University investigates the mixing and segregation of binary and multi-component granular materials. Solids mixing, also known as blending, is a common processing operation used in the manufacture of pharmaceutical products. The intent of mixing...
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Inter- and Intra- Tablet Coating Variability
25 Aug 2024 | Animations
Tablets are coated for a number of reasons, the most important of which is controlling the release profiles and bioavailability of the active pharmaceutical ingredient. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form.Tablets are usually...
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Introduction to API Process Simulation
25 Aug 2024 | Teaching Materials
This module describes model building methods and tools that can be used to simulate unit operations in pharmaceutical API processes. The use of simulation tools is introduced through simulations of heat transfer and fed batch reaction. Models of unit operations are constructed from the balance...
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ParticleVis: A Tool for DEM Particle Visualization
25 Aug 2024 | Downloads
ParticleVis is a visualization tool specialized for loading and exploring particulate simulation data. It contains a set of features that enables powerful and useful visualizations of particle simulations to be quickly generated. Support is provided for visualization of hundreds of thousands of...
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PSL DEM Lecture 01: Motivation
25 Aug 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 01: Motivation.