2019 LyoHUB Annual Report

07 Jun 2019 | Publications | Contributor(s): Carl Wassgren, Avik Sarkar

Creation of Dissolvable Strips Lab - Students and Instructor's Version

19 Aug 2014 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

This is one of a set of experiments designed for lower level undergraduate courses. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives. This contains both a student version and instructor...

Discrete Element Method (DEM) Course Module

01 Jul 2024 | Courses

The DEM course module was created by Carl Wassgren of the Particulate Systems Laboratory (PSL) at Purdue University. The series consists of slides and videos that will familiarize you with the basics of DEM. Discrete Element Method has been applied to analyze and predict flow behaviour in a wide...

Fluidization of Pharmaceutical Substances - Student and Instructor's Versions

01 Jul 2024 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

This is one of a set of experiments designed for lower level undergraduate courses. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives. This contains both a student version and instructor...

High Shear Mixer

01 Jul 2024 | Tools

Analyze particles as they move through a high shear mixer

Hopper Flow Discharge

01 Jul 2024 | Tools

DEM simulation of the discharge of particles from a hopper

Hopper Segregation

01 Jul 2024 | Animations

The Particulate Sciences Laboratory at Purdue University investigates the mixing and segregation of binary and multi-component granular materials. Solids mixing, also known as blending, is a common processing operation used in the manufacture of pharmaceutical products. The intent of mixing...

Hydroproperties of Dissolvable Strips Lab - Student and Instructor's Versions

01 Jul 2024 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

This is one of a set of experiments designed for lower level undergraduate courses that incorporates novel thin films for drug delivery. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives....

Initial vs. Final Height of Dissolvable Strips - Student and Instructor's Versions

01 Jul 2024 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

This is one of a set of experiments designed for lower level undergraduate courses that incorporates novel thin films for drug delivery. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives....

Inter- and Intra- Tablet Coating Variability

01 Jul 2024 | Animations

Tablets are coated for a number of reasons, the most important of which is controlling the release profiles and bioavailability of the active pharmaceutical ingredient. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form.Tablets are usually...

Life Cycle Analysis with Application to Consumer Products and Pharmaceuticals

01 Jul 2024 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

This is a three session module on introduction to performing and interpreting a life cycle analysis using consumer product and pharmaceutical manufacturing examples. Session 1 is an overview of the basic concepts of life cycle analysis. This includes the basics of process modeling and an...

Lyophilization in Review 2019

28 Apr 2020 | Publications | Contributor(s): Carl Wassgren, Avik Sarkar

Summary: In 2019, the U.S. FDA approved a total of 47 lyophilized drug applications submitted by 37 companies. Information on generic drugs was compiled from FDA’s Orange Book database, not including drugs listed with any of the following conditions: discontinued, solution dosage...

Particle and powder technology in pharmaceutical engineering - teaching modules

16 Oct 2012 | Downloads | Contributor(s): Carl Wassgren, Avik Sarkar

Attached are three files. The v-mixer construction file details how to create a v-mixer teaching module for use in the undergraduate curriculum as a way to enhance student's understanding of applications in pharmaceutical engineering. The particle tech labs and demos file is a slide show that...

ParticleVis: A Tool for DEM Particle Visualization

01 Jul 2024 | Downloads

ParticleVis is a visualization tool specialized for loading and exploring particulate simulation data. It contains a set of features that enables powerful and useful visualizations of particle simulations to be quickly generated. Support is provided for visualization of hundreds of thousands of...

Pharmaceutical Bulk Drug Production

01 Jul 2024 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

An ERC educational module. This powerpoint presentation provides an introduction to the essential operations used in the manufacture of pharmaceutical products. The module describes pharmaceutical product life-cycle, variability, testing, and specifications of pharmaceutical ingredients. Unit...

PSL DEM Lecture 01: Motivation

01 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 01: Motivation.

PSL DEM Lecture 02: Hard Particle Collision Modeling

01 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 02: Hard Particle Collision Modeling

PSL DEM Lecture 03: Hard Particle Contact Detection

01 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 03: Hard Particle Contact Detection.

PSL DEM Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I

01 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I.

PSL DEM Lecture 07: Normal Contact Force Models - Part II

01 Jul 2024 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 07: Normal Contact Force Models - Part II.