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2019 LyoHUB Annual Report
07 Jun 2019 | Publications | Contributor(s): Carl Wassgren, Avik Sarkar
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Creation of Dissolvable Strips Lab - Students and Instructor's Version
19 Aug 2014 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar
This is one of a set of experiments designed for lower level undergraduate courses. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives. This contains both a student version and instructor...
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Discrete Element Method (DEM) Course Module
17 Sep 2024 | Courses
The DEM course module was created by Carl Wassgren of the Particulate Systems Laboratory (PSL) at Purdue University. The series consists of slides and videos that will familiarize you with the basics of DEM. Discrete Element Method has been applied to analyze and predict flow behaviour in a wide...
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Drug Delivery Experiments
17 Sep 2024 | Downloads
Attached are five files detailing four separate experiments that are designed to be used in an undergraduate curriculum. The alginate bead experiment utilizes an alginate hydrogel drug delivery system to affect the rate at which a dye or protein is released. The lozenge experiment is a drug...
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Fluidization of Pharmaceutical Substances - Student and Instructor's Versions
17 Sep 2024 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar
This is one of a set of experiments designed for lower level undergraduate courses. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives. This contains both a student version and instructor...
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High Shear Mixer
17 Sep 2024 | Tools
Analyze particles as they move through a high shear mixer
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Hopper Flow Discharge
17 Sep 2024 | Tools
DEM simulation of the discharge of particles from a hopper
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Hopper Segregation
17 Sep 2024 | Animations
The Particulate Sciences Laboratory at Purdue University investigates the mixing and segregation of binary and multi-component granular materials. Solids mixing, also known as blending, is a common processing operation used in the manufacture of pharmaceutical products. The intent of mixing...
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Hydroproperties of Dissolvable Strips Lab - Student and Instructor's Versions
17 Sep 2024 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar
This is one of a set of experiments designed for lower level undergraduate courses that incorporates novel thin films for drug delivery. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives....
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Initial vs. Final Height of Dissolvable Strips - Student and Instructor's Versions
17 Sep 2024 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar
This is one of a set of experiments designed for lower level undergraduate courses that incorporates novel thin films for drug delivery. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives....
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Inter- and Intra- Tablet Coating Variability
17 Sep 2024 | Animations
Tablets are coated for a number of reasons, the most important of which is controlling the release profiles and bioavailability of the active pharmaceutical ingredient. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form.Tablets are usually...
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Life Cycle Analysis with Application to Consumer Products and Pharmaceuticals
17 Sep 2024 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar
This is a three session module on introduction to performing and interpreting a life cycle analysis using consumer product and pharmaceutical manufacturing examples. Session 1 is an overview of the basic concepts of life cycle analysis. This includes the basics of process modeling and an...
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Lyophilization in Review 2019
28 Apr 2020 | Publications | Contributor(s): Carl Wassgren, Avik Sarkar
Summary: In 2019, the U.S. FDA approved a total of 47 lyophilized drug applications submitted by 37 companies. Information on generic drugs was compiled from FDA’s Orange Book database, not including drugs listed with any of the following conditions: discontinued, solution dosage...
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Particle and powder technology in pharmaceutical engineering - teaching modules
16 Oct 2012 | Downloads | Contributor(s): Carl Wassgren, Avik Sarkar
Attached are three files. The v-mixer construction file details how to create a v-mixer teaching module for use in the undergraduate curriculum as a way to enhance student's understanding of applications in pharmaceutical engineering. The particle tech labs and demos file is a slide show that...
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ParticleVis: A Tool for DEM Particle Visualization
17 Sep 2024 | Downloads
ParticleVis is a visualization tool specialized for loading and exploring particulate simulation data. It contains a set of features that enables powerful and useful visualizations of particle simulations to be quickly generated. Support is provided for visualization of hundreds of thousands of...
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Pharmaceutical Bulk Drug Production
17 Sep 2024 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar
An ERC educational module. This powerpoint presentation provides an introduction to the essential operations used in the manufacture of pharmaceutical products. The module describes pharmaceutical product life-cycle, variability, testing, and specifications of pharmaceutical ingredients. Unit...
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PSL DEM Lecture 01: Motivation
17 Sep 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 01: Motivation.
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PSL DEM Lecture 02: Hard Particle Collision Modeling
17 Sep 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 02: Hard Particle Collision Modeling
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PSL DEM Lecture 03: Hard Particle Contact Detection
17 Sep 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 03: Hard Particle Contact Detection.
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PSL DEM Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I
17 Sep 2024 | Teaching Materials
The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I.