This is one of a set of experiments designed for lower level undergraduate courses. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives. This contains both a student version and instructor version.
In this experiment, the students compare three different drug delivery systems for asthma medicines. The students compare the production design of an ADVAIR Diskus® with a metered dose "rescue" inhaler and a nasal spray through a reverse engineering exercise. The second half of this experiment has the students review the quality control aspect of the three devices by taking mass measurements of the doses being delivered and calculating the mean and standard deviation.
The objectives of this experiment are:
Students will learn about intrusive laboratory experiments.
Students will gain experience in reverse engineering strategies and project designs.
Students will conduct a basic quality control analysis operation.
This experiment (and the others in this set) were developed by Rowan University as part of the NSF-funded Engineering Research Center (ERC) for Structured Organic Particulate Systems (SOPS).
Researchers should cite this work as follows:
Alexander Vincent Jannini; David J Krause; Heather Malino; Kevin Sweeney; C.S. Slater PhD; M.J. Savelski PhD (2014), "Asthma Drug Delivery Laboratory Experiment - Student Handout and Instructor's Version," https://pharmahub.org/resources/614.