This is one of a set of experiments designed for lower level undergraduate courses. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives. This contains both a student version and instructor version. In the experiment, the students determine which of the two antacids, Tums® and Alka-Seltzer®, is able to neutralize the most acid. The two antacids are placed in separate model gastric acid solutions, and are then titrated with a basic solution and an indicator. Students determine how much acid was neutralized by the antacid through stoichiometry calculations. The objectives of this experiment are: •Students will perform a back-titration •Students will learn the mechanism of various antacids •Students will gain an understanding of how gastric acid works in the digestive system This experiment (and the others in this set) were developed by Rowan University as part of the NSF-funded Engineering Research Center (ERC) for Structured Organic Particulate Systems (SOPS).

Researchers should cite this work as follows:

• Alexander Vincent Jannini; Dave Krause; Heather Malino; C.S. Slater PhD; M.J. Savelski PhD (2014), "Antacid Comparison Laboratory - Student Handout and Instructor's Version," https://pharmahub.org/resources/606.

  BibTex | EndNote

1. Active pharmaceutical ingredient (API)
2. Excipients
3. Experiments
4. Laboratories
5. undergraduate education