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Wet granulation is a process to assemble particles into a “granule” with improved flow, reduced dust, and other desirable properties. This talk will include an overview of wet granulation, where a spray is added to an agitated powder bed, and recent advances, including the nucleation and granule growth regime maps. These quantitative tools answer two key questions:
1. What do we know about achieving good liquid distribution?
2. What do we know about why different formulations and materials granule differently?
The information provided can be directly applied to understanding, trouble-shooting and scaling-up granulation processes.
(zipped Quicktime movie file)
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