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Lyo Chamber Pressure Variation Calculator

By Alina Alexeenko1, Nikhil Varma2

1. Purdue University 2. AAE

Calculates pressure variation within freeze-dryer shelf as a function of intershelf gap, shelf size and sublimation flux

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Version 1.0 - published on 07 Apr 2015

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Abstract

An analytical model of (Zhang and Liu, 2012)  is used to estimate pressure variation in a freeze-dryer. The model is based on a Poiseuille flow approximation in a channel with a constant sublimation rate on a lower wall. 

Cite this work

Researchers should cite this work as follows:

  • Alina Alexeenko; Nikhil Varma (2015), "Lyo Chamber Pressure Variation Calculator," https://pharmahub.org/resources/pressurevar.

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