Initial vs. Final Height of Dissolvable Strips - Student and Instructor's Versions

10 Apr 2015 | Contributor(s): Alexander Vincent Jannini, Nathan A Haden, Michael Evangelista, C. Stewart Slater, Mariano Savelski

This is one of a set of experiments designed for lower level undergraduate courses that incorporates novel thin films for drug delivery. The focus of the experimental set is to introduce pharmaceutical concepts to undergraduates while also incorporating general engineering educational objectives....

Integrating Pharmaceutical Concepts into Introductory Chemical Engineering Courses - Part I

27 Feb 2010 | Contributor(s): Stephanie Farrell, Mariano J. Savelski, C. Stewart Slater

The following problem sets are designed by Rowan University faculty and students to be used in introductory chemical engineering courses involving basic engineering calculations, material and energy balances. These problems integrate basic terminology and calculations related to pharmaceutical...

Integrating Pharmaceutical Concepts into Introductory Chemical Engineering Courses - Part II

11 Jun 2010 | Contributor(s): Stephanie Farrell, Mariano J. Savelski, C. Stewart Slater

The following problem sets (a continuation of Part I) are designed by Rowan University faculty and students to be used in introductory chemical engineering courses involving basic engineering calculations, material and energy balances. These problems integrate basic terminology and calculations...

Integrating Pharmaceutical Concepts into Introductory Chemical Engineering Courses - Part III

03 Jun 2011 | Contributor(s): Stephanie Farrell, Mariano J. Savelski, C. Stewart Slater

The following problem sets (a continuation of Parts I & II) are designed to be used in introductory chemical engineering courses involving basic engineering calculations, material and energy balances. These problems integrate basic terminology and calculations related to pharmaceutical,...

Introduction to API Process Simulation

24 Sep 2009 | Contributor(s): Kamal Kuriyan

This module describes model building methods and tools that can be used to simulate unit operations in pharmaceutical API processes. The use of simulation tools is introduced through simulations of heat transfer and fed batch reaction. Models of unit operations are constructed from the balance...

Introduction to Mixing Equipment and Processes in Pharmaceutical Operations

13 Feb 2009 | Contributor(s): Piero Armenante, Henrik Pedersen

An ERC SOPS educational module. This powerpoint presentation provides an introduction to the pharmaceutical processing equipment used for liquid-liquid and liquid-solid mixing. The principles of single and multiphase mixing in pharmaceutical processes are introduced along with methods to analyze...

Introduction to solid dosage processing

05 Aug 2013 | Contributor(s): Kamal Kuriyan

This module provides an introduction to solid dosage processing. It highlights the importance of particle properties and their potential impact on the quality attributes of the dosage form. Unit operations and granulation processes that can be used to control particle properties are described....

Introduction to the Rheology of Complex Fluids

19 Feb 2010 | Contributor(s): Aldo Acevedo, Henrik Pedersen

This module contains PowerPoint presentations aimed at providing the necessary background to understand, perform and interpret experimental rheological characterization of complex fluids. An overview of rheology is presented in the first part. Next, the available instrumentation and typical flows...

Life Cycle Analysis with Application to Consumer Products and Pharmaceuticals

17 Dec 2011 | Contributor(s): C. Stewart Slater

This is a three session module on introduction to performing and interpreting a life cycle analysis using consumer product and pharmaceutical manufacturing examples. Session 1 is an overview of the basic concepts of life cycle analysis. This includes the basics of process modeling and an...

Liquid Mixing Fundamentals

13 Feb 2009 | Contributor(s): Piero Armenante, Henrik Pedersen

An ERC SOPS educational module. This powerpoint presentation provides background to identify the geometric, physical and dynamic variables of importance for the analysis of mixing in a stirred tank. It inroduces methods to assess the relative importance of those variables and toquantify the power...

Model Driven Product Development for the 21st Century

16 Apr 2014 | Contributor(s): Adam Fermier

Model driven product development is quite complex problem that will require a diverse group of experts to collaborate on a frame work to achieve said goal. That frame work should establish:* Methodology to describe a process (e.g., a recipe, decision tree or workflow)* Semantic methodology to...

NIR Fundamentals and " a little more"

20 Dec 2011 | Teaching Materials | Contributor(s): Rodofo J Romanach

These slides have been prepared by three graduate students with the objective of facilitating teaching NIR to students who are starting to do research in the field.These slides are based on the use of NIR as a characterization method for solids. Thus they are focused on the basics and diffuse...

NIR Spectroscopy: An Advanced Alternative

20 Dec 2011 | Teaching Materials | Contributor(s): Rodofo J Romanach

This set of slides has been prepared with by three graduate students with the objective of facilitating teaching NIR to students who are starting to do research in the field.These slides are based on the use of NIR as a characterization method for solids. Thus they are focused on the basics and...

Particle and Powder Flow Characterization

27 Feb 2010 | Teaching Materials | Contributor(s): Carl Wassgren, Henrik Pedersen

An ERC education module, developed by Professor Raj Dave, NJIT. This module includes contributions from a number of investigators and introduces characterization methods and theory for particles and powders.Raj Dave, NJIT

Particle Processing and Modeling in the Pharmaceutical Industry

19 Feb 2010 | Teaching Materials | Contributor(s): Benjamin Glasser, Henrik Pedersen

An ERC educational module. Prepared by Professor Ben Glasser, Rutgers University.

Pharmaceutical Bulk Drug Production

13 Feb 2009 | Teaching Materials | Contributor(s): Benjamin Glasser, Henrik Pedersen

An ERC educational module. This powerpoint presentation provides an introduction to the essential operations used in the manufacture of pharmaceutical products. The module describes pharmaceutical product life-cycle, variability, testing, and specifications of pharmaceutical ingredients. Unit...

Pharmaceutical Dissolution Testing

19 Feb 2010 | Teaching Materials | Contributor(s): Bo Hu, Henrik Pedersen

Dissolution testing is a critical formulation tool in the process of drug discovery that entails measuring the stability of the investigational product, achieving uniformity in production lots and determining its in vivo availability. Thus this method is useful in the pharmaceutical and...

Pharmacokinetic based design of individualized dosage regimens

10 May 2011 | Teaching Materials | Contributor(s): Jose Miguel Lainez, Gary Blau, Linas Mockus, Seza Orcun, Rex Reklaitis

Clinical trials and health care studies generate an enormous amount of data. This data is used by pharmaceutical companies during new drug development processes to characterize patient populations and determine a standardized dosage regimen for new patients. Nevertheless, the knowledge embedded...

Probability Theory Review

05 May 2008 | Teaching Materials | Contributor(s): Gary Blau

For any real system or phenomenon, there will be a certain amount of variability associated with data generated by the system.Probability is the language used to characterize and interpret the variability of this data.Probability is the most widely used formalism for quantifying uncertainty.

Problems for Statistical Model Building

05 May 2008 | Teaching Materials | Contributor(s): Gary Blau

Scenarios, problem statements, JMP data files, and solutions for the course on Statistical Model Building and Design of Experiments. Scenario 1 is based on a batch reactor system for small molecule API production. Scenario 2 is based on a test-bed to study the feasibility of continuous operation...