Introduction to Mixing Equipment and Processes in Pharmaceutical Operations

13 Feb 2009 | Contributor(s): Piero Armenante, Henrik Pedersen

An ERC SOPS educational module. This powerpoint presentation provides an introduction to the pharmaceutical processing equipment used for liquid-liquid and liquid-solid mixing. The principles of single and multiphase mixing in pharmaceutical processes are introduced along with methods to analyze...

Colloids and Surfactants

13 Feb 2009 | Contributor(s): Paul Takhistov, Henrik Pedersen

An ERC SOPS educational module. An introduction to colloids and surfactants with an emphasis on the physical factors affecting formation. The module also introduces several applications of colloids and surfactants.Paul Takhistov is an Associate professor of Food Science at Rutgers University, New...

Pharmaceutical Bulk Drug Production

13 Feb 2009 | Contributor(s): Benjamin Glasser, Henrik Pedersen

An ERC educational module. This powerpoint presentation provides an introduction to the essential operations used in the manufacture of pharmaceutical products. The module describes pharmaceutical product life-cycle, variability, testing, and specifications of pharmaceutical ingredients. Unit...

Computational Methods for Molecular Crystals - Lectures and Downloads

04 Nov 2008 | Teaching Materials | Contributor(s): Stephan X.M. Boerrigter

The presentation slides contain written narration in the notes page view. A separate word document is provided that contains the same notes.movies.zip contains a collection of movie files. These movies will play within the presentation when clicked on them. This only works when the movies are...

PSL DEM Lecture 11: Coarse Contact Detection

15 May 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 11: Coarse Contact Detection.

PSL DEM Lecture 09: Tangential Contact Force Models

15 May 2008 | Teaching Materials

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 9: Tangential Contact Force Models.

Problems for Statistical Model Building

05 May 2008 | Teaching Materials | Contributor(s): Gary Blau

Scenarios, problem statements, JMP data files, and solutions for the course on Statistical Model Building and Design of Experiments. Scenario 1 is based on a batch reactor system for small molecule API production. Scenario 2 is based on a test-bed to study the feasibility of continuous operation...

Response Surface Methodology

05 May 2008 | Teaching Materials | Contributor(s): Gary Blau

This lecture describes response surface models:Models are simple polynomialsInclude terms for interaction and curvatureCoefficients are usually established by regression analysis with a computer programInsignificant terms are discarded

Screening

05 May 2008 | Teaching Materials | Contributor(s): Gary Blau

The objectives of this lecture are to:Show how to screen or select the most important main effects with fewer experiments.Show how to construct fractional factorial experiments by sacrificing interactionsUnderstand the concept of confounding / aliasesLearn how to write the mathematical model for...

Factorial Experimentation

05 May 2008 | Teaching Materials | Contributor(s): Gary Blau

A full factorial experiment is a set of experimental runs such that all levels of a given factor are combined with all levels of every other factor.

Single Factor Experiments

05 May 2008 | Teaching Materials | Contributor(s): Gary Blau

The purpose of single factor experiments is to:Quantify relationship between a single factor and a single measured or response variableCompare the relative effectiveness of two or more treatments (levels of the factor).Estimate the level of the factor that optimizes the response variable

Review of Statistics

05 May 2008 | Teaching Materials | Contributor(s): Gary Blau

This lecture covers the following topicsDifference between statistics and probabilityStatistical InferenceSamples and populationsIntro to JMP software packageCentral limit theoremConfidence intervalsHypothesis testingRegression and modeling fundamentalsIntroduction to Model BuildingSimple linear...

Probability Theory Review

05 May 2008 | Teaching Materials | Contributor(s): Gary Blau

For any real system or phenomenon, there will be a certain amount of variability associated with data generated by the system.Probability is the language used to characterize and interpret the variability of this data.Probability is the most widely used formalism for quantifying uncertainty.

PSL DEM Lecture 13: 3D Rotations

26 Jan 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 13: 3D Rotations.

PSL DEM Lecture 07: Normal Contact Force Models - Part II

26 Jan 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 07: Normal Contact Force Models - Part II.

PSL DEM Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I

26 Jan 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I.

PSL DEM Lecture 02: Hard Particle Collision Modeling

26 Jan 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 02: Hard Particle Collision Modeling

PSL DEM Lecture 03: Hard Particle Contact Detection

26 Jan 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 03: Hard Particle Contact Detection.

PSL DEM Lecture 01: Motivation

26 Jan 2008 | Teaching Materials | Contributor(s): Carl Wassgren, Avik Sarkar

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 01: Motivation.