NIR Spectroscopy: An Advanced Alternative

20 Dec 2011 | Teaching Materials | Contributor(s): Rodofo J Romanach

This set of slides has been prepared with by three graduate students with the objective of facilitating teaching NIR to students who are starting to do research in the field.These slides are based on the use of NIR as a characterization method for solids. Thus they are focused on the basics and...

Life Cycle Analysis with Application to Consumer Products and Pharmaceuticals

17 Dec 2011 | Teaching Materials | Contributor(s): C. Stewart Slater

This is a three session module on introduction to performing and interpreting a life cycle analysis using consumer product and pharmaceutical manufacturing examples. Session 1 is an overview of the basic concepts of life cycle analysis. This includes the basics of process modeling and an...

Integrating Pharmaceutical Concepts into Introductory Chemical Engineering Courses - Part III

03 Jun 2011 | Teaching Materials | Contributor(s): Stephanie Farrell, Mariano J. Savelski, C. Stewart Slater

The following problem sets (a continuation of Parts I & II) are designed to be used in introductory chemical engineering courses involving basic engineering calculations, material and energy balances. These problems integrate basic terminology and calculations related to pharmaceutical,...

Pharmacokinetic based design of individualized dosage regimens

10 May 2011 | Teaching Materials | Contributor(s): Jose Miguel Lainez, Gary Blau, Linas Mockus, Seza Orcun, Rex Reklaitis

Clinical trials and health care studies generate an enormous amount of data. This data is used by pharmaceutical companies during new drug development processes to characterize patient populations and determine a standardized dosage regimen for new patients. Nevertheless, the knowledge embedded...

Integrating Pharmaceutical Concepts into Introductory Chemical Engineering Courses - Part II

11 Jun 2010 | Teaching Materials | Contributor(s): Stephanie Farrell, Mariano J. Savelski, C. Stewart Slater

The following problem sets (a continuation of Part I) are designed by Rowan University faculty and students to be used in introductory chemical engineering courses involving basic engineering calculations, material and energy balances. These problems integrate basic terminology and calculations...

Wet granulation: Understanding granule formation and growth

25 May 2010 | Teaching Materials | Contributor(s): Karen P Hapgood

Wet granulation is a process to assemble particles into a “granule” with improved flow, reduced dust, and other desirable properties. This talk will include an overview of wet granulation, where a spray is added to an agitated powder bed, and recent advances, including the nucleation and granule...

Integrating Pharmaceutical Concepts into Introductory Chemical Engineering Courses - Part I

27 Feb 2010 | Teaching Materials | Contributor(s): Stephanie Farrell, Mariano J. Savelski, C. Stewart Slater

The following problem sets are designed by Rowan University faculty and students to be used in introductory chemical engineering courses involving basic engineering calculations, material and energy balances. These problems integrate basic terminology and calculations related to pharmaceutical...

Particle and Powder Flow Characterization

27 Feb 2010 | Teaching Materials | Contributor(s): Carl Wassgren, Henrik Pedersen

An ERC education module, developed by Professor Raj Dave, NJIT. This module includes contributions from a number of investigators and introduces characterization methods and theory for particles and powders.Raj Dave, NJIT

Introduction to the Rheology of Complex Fluids

19 Feb 2010 | Teaching Materials | Contributor(s): Aldo Acevedo, Henrik Pedersen

This module contains PowerPoint presentations aimed at providing the necessary background to understand, perform and interpret experimental rheological characterization of complex fluids. An overview of rheology is presented in the first part. Next, the available instrumentation and typical flows...

Pharmaceutical Dissolution Testing

19 Feb 2010 | Teaching Materials | Contributor(s): Bo Hu, Henrik Pedersen

Dissolution testing is a critical formulation tool in the process of drug discovery that entails measuring the stability of the investigational product, achieving uniformity in production lots and determining its in vivo availability. Thus this method is useful in the pharmaceutical and...

Application of Chemical Engineering Principles to Drug Delivery

19 Feb 2010 | Teaching Materials | Contributor(s): Madeline Torres-Lugo, Henrik Pedersen

An ERC SOPS educational module highlighting the appropriate administration of drugs through various routes in the body for the purpose of improving health. The approach is highly interdisciplinary, not a young field and it has recently evolved to take into consideration drug physico-chemical...

Vibrational Spectroscopy for Pharmaceutical Analysis

19 Feb 2010 | Teaching Materials | Contributor(s): Rodolfo Romañach, Henrik Pedersen

An ERC educational module prepared by Professor Rodolfo J. Romañach, UPRM. A series of 10 powerpoint presentations introduce the topic of vibrational spectroscopy with particular relevance to pharmaceutical analysis and manufacturing.Rodolfo J. Romañach, UPRM

Particle Processing and Modeling in the Pharmaceutical Industry

19 Feb 2010 | Teaching Materials | Contributor(s): Benjamin Glasser, Henrik Pedersen

An ERC educational module. Prepared by Professor Ben Glasser, Rutgers University.

Solid-Liquid Separations

24 Sep 2009 | Teaching Materials | Contributor(s): Kamal Kuriyan

This module covers topics related to solid-liquid separations:Flow in packed beds.Cake filtration.Centrifuges.Deliquoring and washing.

Applications: Solvent Switching

24 Sep 2009 | Teaching Materials | Contributor(s): Kamal Kuriyan

This module presents an application of a simulation model in API process development and design. The application involves the use of a simulation model to compare feed profiles for solvent switching in a batch vessel.ERC for Structured Organic Particulate Systems

Batch Distillaton Basics

24 Sep 2009 | Teaching Materials | Contributor(s): Kamal Kuriyan

This module introduces topics related to batch distillation:Vapor-liquid equilibrium.Single stage distillation.Column configuration and operating policies.Simulation and design of distillation columns.Girish Joglekar

Introduction to API Process Simulation

24 Sep 2009 | Teaching Materials | Contributor(s): Kamal Kuriyan

This module describes model building methods and tools that can be used to simulate unit operations in pharmaceutical API processes. The use of simulation tools is introduced through simulations of heat transfer and fed batch reaction. Models of unit operations are constructed from the balance...

Sterilization and Disinfection

13 Feb 2009 | Teaching Materials | Contributor(s): Piero Armenante, Henrik Pedersen

An ERC SOPS educational module. This powerpoint presentation provides an overview of sterilization and disinfection processes relevant to pharmaceutical manufacturing. The definitions, applicable regulatory guidelines and methods are described for a variety of alternative strategies.Piero...

Characterization of Nanopharmaceutical Materials

13 Feb 2009 | Teaching Materials | Contributor(s): Boris Khusid, Henrik Pedersen

An ERC SOPS educational module. This powerpoint presentation provides an overview of the tools, instruments and methods for analysis and characterization of nanopharmaceutical materials.Boris Khusid is a Professor in the Department of Chemical and Biopharmaceutical Engineering at NJIT, Newark, NJ

Liquid Mixing Fundamentals

13 Feb 2009 | Teaching Materials | Contributor(s): Piero Armenante, Henrik Pedersen

An ERC SOPS educational module. This powerpoint presentation provides background to identify the geometric, physical and dynamic variables of importance for the analysis of mixing in a stirred tank. It inroduces methods to assess the relative importance of those variables and toquantify the power...