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Online Simulation

And More

  1. Knowledge-based systems
  2. Discrete element model (DEM)
  3. QbD presentation
  4. Van der waals force
  5. Particle adhesion
  6. Process modeling
  7. Hamaker constants
  8. Roller compaction
  9. Particle-based computations
  10. Johanson's model
  11. Statistical model building
  12. Molecular modeling
  13. Dry granulation
  14. Visualization
  15. Excipients
  16. Database
  17. Active pharmaceutical ingredient (API)

Other

Databases

Category Online Presentations
Abstract

The development of a pharmaceutical product requires the collection of information during pre-formulation studies, product formulation, process development, scaleup and manufacturing. A large amount of information of different types, ranging from raw data to lab reports to sophisticated math models, has to be shared, utilized and modified by humans for decision making. This functionality requires an informatics infrastructure which supports different activities by streamlining information gathering, data integration, model development and decision making (Venkatasubramanian et al, 2006). The foundation of such an infrastructure is the explicitly and formally modeled information, called an ontology.

The Purdue Ontology for Pharmaceutical Engineering is presented here. Information is captured in the form of concepts and the relations between concepts. The ontology is centered on the concepts of materials, experiments and properties and builds on previous work. Through the definition of the ontology, several functions that are difficult to perform like complicated searches, association storage and reasoning are made available.

Contributor Ann Christine Catlin
  • super-administrator
Cite this work

Researchers should cite this work as follows:

  • Venkat Venkatasubramanian; Leaelaf Hailemariam; Rex Reklaitis; Pradeep Suresh (2008), "Information Representation in POPE," http://pharmahub.org/resources/90.

    BibTex | EndNote

Tags
  1. Knowledge-based systems