1. Gabapentin Population Model for PK Parameter Individualization

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   12 Sep 2011 | Tools | Contributor(s): Jose Miguel Lainez, Linas Mockus, Gary Blau, Seza Orcun, Rex Reklaitis

   Generates individual PK parameters based on few samples and the population prior

2. Dose regimen individualization

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   24 Aug 2011 | Tools | Contributor(s): Jose Miguel Lainez, Linas Mockus, Gary Blau, Seza Orcun, Rex Reklaitis

   Dose regimen individualization

3. Pharmacokinetic based design of individualized dosage regimens

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   10 May 2011 | Teaching Materials | Contributor(s): Jose Miguel Lainez, Gary Blau, Linas Mockus, Seza Orcun, Rex Reklaitis

   Clinical trials and health care studies generate an enormous amount of data. This data is used by pharmaceutical companies during new drug development processes to characterize patient populations and determine a standardized dosage regimen for new patients. Nevertheless, the knowledge embedded in …

4. Introduction to Model Building

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   08 May 2008 | Online Presentations | Contributor(s): Gary Blau

   Course Background: Initial ideas developed for Pharmaceutical Scientists at the Dow Chemical Plant in Brindisi, Italy (1975) Subsequently evolved into a global course on Process Optimization presented to Dow Scientists and engineers in Europe and North America. Morphed into two courses in …

5. Problems for Statistical Model Building

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   05 May 2008 | Teaching Materials | Contributor(s): Gary Blau

   Scenarios, problem statements, JMP data files, and solutions for the course on Statistical Model Building and Design of Experiments. Scenario 1 is based on a batch reactor system for small molecule API production. Scenario 2 is based on a test-bed to study the feasibility of continuous operation …

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