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LyoHUB 2023 Annual Meeting Recording one_morning session
01 May 2023 | Online Presentations
LyoHUB 2023 Annual Meeting recording part one
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LyoHUB Membership presentation
01 Oct 2020 | Online Presentations | Contributor(s): Jennifer Gray
slides for those interested in membership
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Jos Corver lecture on Continuous Freeze Drying
14 Feb 2019 | Online Presentations | Contributor(s): Jos Corver
Jos Corver December 2018 lecture on Continuous Freeze Drying for LyoHUB at Purdue University can be viewed at http://www.kaltura.com/tiny/z0puf ABSTRACT: The guidelines of FDA’s PAT mention the need for continuous processing in pharma to achieve a mechanism of 100%...
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Recommended Best Practices for Process Instrumentation in Freeze Drying
28 Jan 2019 | Online Presentations | Contributor(s): Steven L Nail
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Fundamentals of Freeze Drying: A Brief Review and Commentary
11 Jan 2019 | Online Presentations | Contributor(s): Steven L Nail
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Introduction to CFD
18 Dec 2018 | Online Presentations | Contributor(s): David Russ
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Fundamentals of Freeze Drying II: The Freezing Process
18 Dec 2018 | Online Presentations | Contributor(s): Steven L Nail
OutlineThe Freezing ProcessSupercooling and ice nucleationCharacterization of freezing behaviorEstablishment of upper product temperature limit during primary drying
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Fundamentals of Freeze Drying V: Formulation Consderations
30 Nov 2018 | Online Presentations | Contributor(s): Steven L Nail
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Fundamentals of Freeze Drying IV: Process Monitoring
30 Nov 2018 | Online Presentations | Contributor(s): Steven L Nail
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Fundamentals of Freeze Drying III: Primary and Secondary Drying
30 Nov 2018 | Online Presentations | Contributor(s): Steven L Nail
OutlinePrimary dryingHeat transfer considerationsMeasurement of the vial heat transfer coefficientMass transfer considerationsMeasurement of the resistance of the dried product layerSecondary dryingCritical process variables during secondary dryingHow dry is “dry enough”
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Fundamentals of Freeze Drying I: Introduction and Process Overview
30 Nov 2018 | Online Presentations | Contributor(s): Steven L Nail
Outline Introduction Advantages and limitations of freeze drying Product quality attributes Process overview Freezing Primary drying Secondary drying The Freezing Process Supercooling and ice nucleation Characterization of freezing...
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Progress in Vacuum Pressure Measurement
08 Nov 2018 | Online Presentations | Contributor(s): Martin Wuest
For many years standard vacuum pressure measurement sensors consist of capacitance diaphragm gauges, Pirani heat transfer gauges as well as ionization gauges. Development has progressed from passive gauges with a detached controller to combination gauges with integrated electronics. Market...
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Dr. Michael Pikal presentation "Modeling in Freeze-Drying:Past, Current State and Future Perspectives"
27 Jun 2018 | Online Presentations
Early Work by Marcus KarelMotivation for Modeling StudiesStead State ModelsThe Non-Steady State Model in Two DimensionsNon-Steady Models for Sublimation and Desorption DryingThe Nonsteady State Modeling of Freeze Drying: In-Process Product Temperature and Moisture Content...
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Developing Transferable Freeze Drying Protocols Using Accuflux® and a MicroFD®
06 Feb 2017 | Online Presentations | Contributor(s): Taylor N Thompson
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LyoHUB Membership PowerPoint
20 Jul 2016 | Online Presentations | Contributor(s): Jennifer Gray
LyoHUB presentation on Who we are and Benefits of Joining this consortium
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LyoHUB Demo Facility PowerPoint 1
01 Jun 2016 | Online Presentations | Contributor(s): Jennifer Gray, Alina Alexeenko
This Powerpoint allows the viewer to see photos and descriptions of items currently in the LyoHUB Demonstration Facility. It will be updated regularly.
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Trends in Solvent Management in the Pharmaceutical Industry
18 Jul 2013 | Online Presentations | Contributor(s): Mariano J. Savelski, C. Stewart Slater
The optimization of solvent use and the reduction of waste generation in pharmaceutical industry, have become key elements in the improvement of the overall environmental footprint . Solvent selection and solvent substitution practices, elimination of hazardous solvents, and purification, reuse...
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Life Cycle Analysis of Biobased Pennakem's ecoMeTHF™ : Green Solvents for the Pharmaceutical and Fine Chemical Industry
18 Jul 2013 | Online Presentations | Contributor(s): Mariano Savelski, C. Stewart Slater, Dave Aycock, Bogdan Comanita, Steve Prescott, Jeff Shifflette, Rowan University
An environmental analysis has been conducted to determine the life cycle emissions to manufacture the green solvent, 2-methyltetrahydrofuran. Analyses have been performed using different methods to show greenness in both its production and industrial use. This solvent has the potential as a...
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LCA approach to the analysis of solvent waste issues in the pharmaceutical industry
18 Jul 2013 | Online Presentations | Contributor(s): Michael Raymond, C. Stewart Slater, Mariano J. Savelski
Life cycle assessment offers a unique opportunity to analyze emission reductions across all manufacturing sectors. However, few efforts have been made to apply this method to the pharmaceutical industry. Typically, between 80 and 90% of the total mass used in the production of an active...
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University Engineering Clinics to Advance Green Engineering in Pharmaceutical Production
18 Jul 2013 | Online Presentations | Contributor(s): C. Stewart Slater, Mariano J. Savelski, Rowan University
Rowan Chemical Engineering faculty and students are using their “engineering clinic” program to examine active pharmaceutical ingredient (API) syntheses for sustainable design opportunities. Solvent use and waste reduction strategies are the primary area the group has investigated for the...