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  1. Guidelines Viewer

    05 Mar 2009 |

    View Guidelines in Ontology Browser

  2. Information Representation in POPE

    23 Jan 2008 | | Contributor(s):: venkat, laelaf, Rex Reklaitis, pradeepsuresh

    The development of a pharmaceutical product requires the collection of information during pre-formulation studies, product formulation, process development, scaleup and manufacturing. A large amount of information of different types, ranging from raw data to lab reports to sophisticated math...

  3. Navigating the POPE Ontology

    21 Jan 2008 | | Contributor(s):: laelaf, venkat

    What knowledge is included in POPE? There are three knowledge components: guideline knowledge, mathematical knowledge and information representations. The guideline knowledge component includes representations of actions and decisions. The mathematical knowledge component includes descriptions of...

  4. Ontological informatics infrastructure for pharmaceutical product development

    17 Jan 2008 | | Contributor(s):: venkat, Rex Reklaitis, laelaf, pradeepsuresh

    Informatics infrastructure plays a crucial role in supporting different decision making activities related to pharmaceutical product development, pilot plant and commercial scale manufacturing by streamlining information gathering, data integration, model development and managing all these for...

  5. Ontological Informatics Infrastructure: An Overview

    23 Jan 2008 | | Contributor(s):: venkat, Rex Reklaitis, laelaf, pradeepsuresh

    Pharmaceutical product development involves managing a large amount of information and knowledge in different formats. Ontological informatics is used to represent and integrate the information and knowledge and support product development applications.Venkat Venkatasubramanian,Chunhua Zhao,...

  6. Pharmaceutical Informatics

    30 Dec 2007 | | Contributor(s):: venkat, Rex Reklaitis, laelaf, shsu, pradeepsuresh

    Pharmaceutical products manufacturing is an important growth area for the US economy. Continued progress in biotechnology and genetic engineering coupled with an aging population will create both new mega-opportunities as well as pose new major challenges in this area, where the products are...

  7. Product Formulation

    23 Jan 2008 | | Contributor(s):: venkat, laelaf, pradeepsuresh

    Pharmaceutical product development involves drug discovery,development of the drug substance (for improved processibility and absorption), anddevelopment of the drug product (identity and amount of excipients, choice of manufacturing platform or process).Product development requires access to...

  8. Purdue Ontology for Pharmaceutical Engineering

    21 Jan 2008 | | Contributor(s):: laelaf, venkat, shsu, pradeepsuresh

    Web Ontology Language (OWL), recommended by and based from Resource Description Framework (W3C), is used to define ontologies. OWL uses XML syntax to express semantics. OWL can formalize a domain by defining classes, properties of these classes, and relations between them. OWL can also define...

  9. SWOOP

    16 Jan 2008 | | Contributor(s):: d s  k, laelaf, shsu, pradeepsuresh

    OWL Ontology Editor

  10. Towards intelligent decision support for pharmaceutical product development

    17 Jan 2008 | | Contributor(s):: venkat, Rex Reklaitis, laelaf, pradeepsuresh

    Developing pharmaceutical product formulation in a timely manner and ensuring quality is a complex process that requires a systematic, science-based approach. Information from various categories, including properties of the drug substance and excipients, interactions between materials, unit...