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  1. Alkaline Penicillin G Hydrolysis

    24 Sep 2013 | Tools | Contributor(s): Lee Kirsch, Stephen Dion Stamatis

    Simulate hydrolysis of penicillin G

  2. Rowan University's Scientific Journal Articles on Green Engineering in Pharmaceutical Production

    19 Aug 2013 | Publications | Contributor(s): Rowan University , C. Stewart Slater, Mariano J. Savelski

    Rowan University has partnered with the pharmaceutical industry through the US EPA Region 2 Pollution Prevention program to explore green engineering approaches in drug manufacturing. Rowan Chemical Engineering faculty and students are using their “engineering clinic” program to examine active...

  3. Introduction to solid dosage processing

    24 Jul 2013 | Teaching Materials | Contributor(s): Kamal Kuriyan

    This module provides an introduction to solid dosage processing. It highlights the importance of particle properties and their potential impact on the quality attributes of the dosage form. Unit operations and granulation processes that can be used to control particle properties are described....

  4. Trends in Solvent Management in the Pharmaceutical Industry

    09 Jul 2013 | Online Presentations | Contributor(s): Mariano J. Savelski, C. Stewart Slater

    The optimization of solvent use and the reduction of waste generation in pharmaceutical industry, have become key elements in the improvement of the overall environmental footprint . Solvent selection and solvent substitution practices, elimination of hazardous solvents, and purification, reuse...

  5. Life Cycle Analysis of Biobased Pennakem's ecoMeTHF™ : Green Solvents for the Pharmaceutical and Fine Chemical Industry

    09 Jul 2013 | Online Presentations | Contributor(s): Mariano Savelski, C. Stewart Slater, Dave Aycock, Bogdan Comanita, Steve Prescott, Jeff Shifflette, Rowan University

    An environmental analysis has been conducted to determine the life cycle emissions to manufacture the green solvent, 2-methyltetrahydrofuran. Analyses have been performed using different methods to show greenness in both its production and industrial use. This solvent has the potential as a...

  6. LCA approach to the analysis of solvent waste issues in the pharmaceutical industry

    09 Jul 2013 | Online Presentations | Contributor(s): Michael Raymond, C. Stewart Slater, Mariano J. Savelski

    Life cycle assessment offers a unique opportunity to analyze emission reductions across all manufacturing sectors. However, few efforts have been made to apply this method to the pharmaceutical industry. Typically, between 80 and 90% of the total mass used in the production of an active...

  7. University Engineering Clinics to Advance Green Engineering in Pharmaceutical Production

    09 Jul 2013 | Online Presentations | Contributor(s): C. Stewart Slater, Mariano J. Savelski, Rowan University

    Rowan Chemical Engineering faculty and students are using their “engineering clinic” program to examine active pharmaceutical ingredient (API) syntheses for sustainable design opportunities. Solvent use and waste reduction strategies are the primary area the group has investigated for the...

  8. Green Process Analysis for Solvent Reduction in Pharmaceutical Synthesis

    09 Jul 2013 | Online Presentations | Contributor(s): C. Stewart Slater, Mariano J. Savelski, Rowan University

    Rowan Chemical Engineering faculty and students are using their “engineering clinic” program to examine active pharmaceutical ingredient (API) syntheses for pollution prevention opportunities. Solvent use and waste reduction strategies are the primary area the group has investigated for the...

  9. Partnerships between Academia and the Pharmaceutical Industry to Advance Green Engineering

    09 Jul 2013 | Online Presentations | Contributor(s): C. Stewart Slater, Mariano J. Savelski, Rowan University

    Rowan University is partnering with the pharmaceutical industry through the US EPA Region 2 Pollution Prevention program to explore green engineering approaches in drug manufacturing. Rowan Chemical Engineering faculty and students are using their "engineering clinic" program to examine active...

  10. Green Engineering Challenged and Opportunities in the Pharmaceutical Industry

    03 Jul 2013 | Online Presentations | Contributor(s): C. Stewart Slater, Mariano J. Savelski, Robert P. Hesketh, Rowan University

    This overview of the pharmaceutical industry focuses on the manufacturing operations that present challenges from an environmental standpoint. These topics include the issues related to drug synthesis and how green engineering principles can be integrated from drug design to manufacturing. These...

  11. Workflow Editor

    06 Mar 2013 | Tools | Contributor(s): Girish S Joglekar, George A. Howlett, Arun Giridhar

    Workflow Editor

  12. Opening Your Mind To Vibrational Spectroscopy

    14 Mar 2013 | Online Presentations | Contributor(s): Rodolfo J Romañach

    Short Presentation on NIR Spectroscopy

  13. From PCA to Regression: Following the Guiding Discipline

    14 Mar 2013 | Online Presentations | Contributor(s): Rodolfo J Romañach

    Short presentation on NIR Spectroscopy

  14. Continuous Manufacturing and Green Chemistry Alternative

    14 Mar 2013 | Teaching Materials | Contributor(s): Dr. Angela Gonzalez, Dr. Rodolfo J Romañach

    Dr. Angela González teaches a Green Chemistry course at the Interamerican University in San German, and thanks to her initiative the following presentations and discussion questions have been developed linking three topics: PAT, continuous manufacturing, and green chemistry. The first principle...

  15. Integrating Pharmaceutical Engineering Topics into Chemical Engineering - Workshop

    13 Sep 2012 | Downloads | Contributor(s): Stephanie Farrell, Zenaida O. Gephardt, Mariano J. Savelski, C. Stewart Slater

    This workshop consists of an interactive presentation integrated with example problem and demonstrations to teach concepts of pharmaceutical engineering relevant to core chemical engineering principles such as material and energy balances, transport phenomena, and materials. An introduction will...

  16. Drug Delivery Experiments

    11 Sep 2012 | Downloads | Contributor(s): Stephanie Farrell

    Attached are five files detailing four separate experiments that are designed to be used in an undergraduate curriculum. The alginate bead experiment utilizes an alginate hydrogel drug delivery system to affect the rate at which a dye or protein is released. The lozenge experiment is a drug...

  17. Particle and powder technology in pharmaceutical engineering - teaching modules

    13 Sep 2012 | Downloads | Contributor(s): Zenaida Otero Gephardt

    Attached are three files. The v-mixer construction file details how to create a v-mixer teaching module for use in the undergraduate curriculum as a way to enhance student's understanding of applications in pharmaceutical engineering. The particle tech labs and demos file is a slide show that...

  18. Workshop on Pharmaceutical Engineering for Undergraduate Engineering Education

    11 Sep 2012 | Downloads | Contributor(s): Mariano J. Slavelski, C. Stewart Slater

    This download contains lecture slides that were used during a workshop at the American Society of Engineering Education (ASEE) Summer School, held in Orono, Maine from July 21-26, 2012. The goal of this download is to present the essential elements of pharmaceutical engineering relevant to...

  19. Distillation Viewer for Multicomponent Separations

    27 Jan 2012 | Tools | Contributor(s): Joshua Huff, Gautham Madenoor Ramapriya, George A. Howlett, Anirudh Arun Shenvi, Mohit Tawarmalani, Rakesh Agrawal, Haibo Zhang

    Graphical interface to examine configurations generated by NLP distillation optimization

  20. Advance Process Control I

    26 Jan 2011 | Online Presentations | Contributor(s): Carlos Velazquez