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  Tazzle 20 mg should be taken about 30 minutes to 1 hour before anticipated sexual activity. It's important to note that the medication does not automatically cause an erection; sexual stimulation is still necessary for it to work effectively. It's essential to follow your healthcare provider's instructions when taking Tazzle 20 mg. Avoid consuming alcohol or grapefruit products while using this medication, as they can interfere with its effectiveness. Inform your healthcare provider about any medical conditions you have and any other medications you are taking to avoid potential interactions.