Gabapentin Population Model for PK Parameter Individualization

12 Sep 2011 | Tools | Contributor(s): Jose Miguel Lainez, Linas Mockus, Gary Blau, Seza Orcun, Rex Reklaitis

Generates individual PK parameters based on few samples and the population prior

Dose regimen individualization

24 Aug 2011 | Tools | Contributor(s): Jose Miguel Lainez, Linas Mockus, Gary Blau, Seza Orcun, Rex Reklaitis

Dose regimen individualization

Pharmacokinetic based design of individualized dosage regimens

10 May 2011 | Teaching Materials | Contributor(s): Jose Miguel Lainez, Gary Blau, Linas Mockus, Seza Orcun, Rex Reklaitis

Clinical trials and health care studies generate an enormous amount of data. This data is used by pharmaceutical companies during new drug development processes to characterize patient populations and determine a standardized dosage regimen for new patients. Nevertheless, the knowledge embedded...