Ontological informatics infrastructure for pharmaceutical product development
Posted 16 Jan, 2008 in Publications
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| Contributor(s) | Venkat Venkatasubramanian, Rex Reklaitis, Leaelaf Hailemariam, Pradeep Suresh Purdue University |
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| Abstract | Informatics infrastructure plays a crucial role in supporting different decision making activities related to pharmaceutical product development, pilot plant and commercial scale manufacturing by streamlining information gathering, data integration, model development and managing all these for easy and timely access and reuse. The foundation of such an infrastructure is the explicitly and formally modeled information. This foundation enables knowledge in different forms, and best manufacturing practices, to be modeled and captured into tools to support the product lifecycle management. This paper discusses the development of ontologies, Semantic Web infrastructure and Web related technologies that make such an infrastructure development possible. While many of the issues addressed in this paper are applicable to a wide spectrum of molecular-based products, we focus our work on the development of pharmaceutical informatics to support Active Pharmaceutical Ingredient (API) as well as drug product development as case studies to illustrate the various aspects of this infrastructure. |
| credits | Venkat Venkatasubramanian, Chunhua Zhao, Girish Joglekar, Ankur Jain, Leaelaf Hailemariam, Pradeep Suresh, Pavankumar Akkisetty, Ken Morris and G. V. Reklaitis. Prabir Basu. |
| sponsoredby | The Indiana 21st Century Research and Technology Fund |
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